MGP Database

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MGP002259

Ontology/Pathway Information

Entrez Gene ID5217
Gene Nameprofilin 2
Gene Symbol PFN2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:UniProtKB-KWCcytoplasm
GO:0005856 IEA:UniProtKB-SubCellCcytoskeleton
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0043195 IEA:EnsemblCterminal bouton
GO:0003785 IPI:UniProtKBFactin monomer binding
GO:0000774 IDA:UniProtKBFadenyl-nucleotide exchange factor activity
GO:0005546 IDA:UniProtKBFphosphatidylinositol-4,5-bisphosphate binding
GO:0030036 IEA:InterProPactin cytoskeleton organization
GO:0030837 IDA:UniProtKBPnegative regulation of actin filament polymerization
GO:0010633 IMP:UniProtKBPnegative regulation of epithelial cell migration
GO:1900028 IMP:UniProtKBPnegative regulation of ruffle assembly
GO:0032233 IMP:UniProtKBPpositive regulation of actin filament bundle assembly
GO:0030838 IGI:UniProtKBPpositive regulation of actin filament polymerization
GO:0032781 IDA:UniProtKBPpositive regulation of ATPase activity
GO:0033138 IMP:UniProtKBPpositive regulation of peptidyl-serine phosphorylation
GO:0051496 IMP:UniProtKBPpositive regulation of stress fiber assembly
GO:2000300 IEA:EnsemblPregulation of synaptic vesicle exocytosis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_19351Signaling by Robo receptor
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