MGP Database

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MGP002306

Ontology/Pathway Information

Entrez Gene ID5319
Gene Namephospholipase A2, group IB (pancreas)
Gene Symbol PLA2G1B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:BHF-UCLCcell surface
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0030141 IEA:EnsemblCsecretory granule
GO:0032052 ISS:BHF-UCLFbile acid binding
GO:0047498 IDA:BHF-UCLFcalcium-dependent phospholipase A2 activity
GO:0005509 IDA:BHF-UCLFcalcium ion binding
GO:0004623 IDA:BHF-UCLFphospholipase A2 activity
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0007015 TAS:ProtIncPactin filament organization
GO:0000187 ISS:BHF-UCLPactivation of MAPK activity
GO:0032431 TAS:BHF-UCLPactivation of phospholipase A2 activity
GO:0019731 IDA:UniProtKBPantibacterial humoral response
GO:0050482 TAS:BHF-UCLParachidonic acid secretion
GO:0032869 ISS:BHF-UCLPcellular response to insulin stimulus
GO:0050830 IDA:UniProtKBPdefense response to Gram-positive bacterium
GO:0006633 IDA:BHF-UCLPfatty acid biosynthetic process
GO:0015758 ISS:BHF-UCLPglucose transport
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0002227 IDA:UniProtKBPinnate immune response in mucosa
GO:0032637 ISS:BHF-UCLPinterleukin-8 production
GO:0035556 ISS:BHF-UCLPintracellular signal transduction
GO:0019370 ISS:BHF-UCLPleukotriene biosynthetic process
GO:0044240 IDA:BHF-UCLPmulticellular organismal lipid catabolic process
GO:0030593 ISS:BHF-UCLPneutrophil chemotaxis
GO:0002446 ISS:BHF-UCLPneutrophil mediated immunity
GO:0006654 TAS:ReactomePphosphatidic acid biosynthetic process
GO:0036151 TAS:ReactomePphosphatidylcholine acyl-chain remodeling
GO:0046470 IDA:BHF-UCLPphosphatidylcholine metabolic process
GO:0036152 TAS:ReactomePphosphatidylethanolamine acyl-chain remodeling
GO:0036148 TAS:ReactomePphosphatidylglycerol acyl-chain remodeling
GO:0036149 TAS:ReactomePphosphatidylinositol acyl-chain remodeling
GO:0036150 TAS:ReactomePphosphatidylserine acyl-chain remodeling
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0010524 ISS:BHF-UCLPpositive regulation of calcium ion transport into cytosol
GO:0045740 IDA:BHF-UCLPpositive regulation of DNA replication
GO:0048146 IC:BHF-UCLPpositive regulation of fibroblast proliferation
GO:0050778 ISS:BHF-UCLPpositive regulation of immune response
GO:0051092 ISS:BHF-UCLPpositive regulation of NF-kappaB transcription factor activity
GO:0050714 TAS:BHF-UCLPpositive regulation of protein secretion
GO:0045944 ISS:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0007165 TAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120829Acyl chain remodelling of PC
REACT_121369Acyl chain remodelling of PE
REACT_121324Acyl chain remodelling of PG
REACT_120722Acyl chain remodelling of PI
REACT_121384Acyl chain remodelling of PS
REACT_121401Glycerophospholipid biosynthesis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_120906Synthesis of PA
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