MGP Database

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MGP002307

Ontology/Pathway Information

Entrez Gene ID5320
Gene Namephospholipase A2, group IIA (platelets, synovial fluid)
Gene Symbol PLA2G2A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IDA:LIFEdbCendoplasmic reticulum
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005739 IEA:EnsemblCmitochondrion
GO:0030141 IEA:EnsemblCsecretory granule
GO:0047498 TAS:UniProtKBFcalcium-dependent phospholipase A2 activity
GO:0005509 IEA:InterProFcalcium ion binding
GO:0004623 IDA:BHF-UCLFphospholipase A2 activity
GO:0005543 IDA:BHF-UCLFphospholipid binding
GO:0050830 TAS:BHF-UCLPdefense response to Gram-positive bacterium
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0016042 IEA:UniProtKB-KWPlipid catabolic process
GO:0034374 TAS:BHF-UCLPlow-density lipoprotein particle remodeling
GO:0050680 IEA:EnsemblPnegative regulation of epithelial cell proliferation
GO:0006654 TAS:ReactomePphosphatidic acid biosynthetic process
GO:0046473 IDA:BHF-UCLPphosphatidic acid metabolic process
GO:0036151 TAS:ReactomePphosphatidylcholine acyl-chain remodeling
GO:0036152 TAS:ReactomePphosphatidylethanolamine acyl-chain remodeling
GO:0036148 TAS:ReactomePphosphatidylglycerol acyl-chain remodeling
GO:0036149 TAS:ReactomePphosphatidylinositol acyl-chain remodeling
GO:0036150 TAS:ReactomePphosphatidylserine acyl-chain remodeling
GO:0006644 IDA:BHF-UCLPphospholipid metabolic process
GO:0050729 TAS:BHF-UCLPpositive regulation of inflammatory response
GO:0010744 TAS:BHF-UCLPpositive regulation of macrophage derived foam cell differentiation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0035019 IEA:EnsemblPsomatic stem cell maintenance
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120829Acyl chain remodelling of PC
REACT_121369Acyl chain remodelling of PE
REACT_121324Acyl chain remodelling of PG
REACT_120722Acyl chain remodelling of PI
REACT_121384Acyl chain remodelling of PS
REACT_121401Glycerophospholipid biosynthesis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_120906Synthesis of PA
SMP Pathway Links
SMP IDDescription
SMP00104Indomethacin Action Pathway
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