MGP Database

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MGP002461

Ontology/Pathway Information

Entrez Gene ID5645
Gene Nameprotease, serine, 2 (trypsin 2)
Gene Symbol PRSS2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031012 TAS:UniProtKBCextracellular matrix
GO:0005576 IDA:UniProtKBCextracellular region
GO:0005615 IMP:UniProtKBCextracellular space
GO:0005509 IDA:UniProtKBFcalcium ion binding
GO:0004252 IDA:UniProtKBFserine-type endopeptidase activity
GO:0030574 IDA:UniProtKBPcollagen catabolic process
GO:0007586 IEA:UniProtKB-KWPdigestion
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0045087 TAS:ReactomePinnate immune response
GO:0045785 TAS:UniProtKBPpositive regulation of cell adhesion
GO:0030307 TAS:UniProtKBPpositive regulation of cell growth
GO:0006508 IDA:UniProtKBPproteolysis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118682Activation of Matrix Metalloproteinases
REACT_115574Alpha-defensins
REACT_150401Collagen degradation
REACT_115846Defensins
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
REACT_6900Immune System
REACT_6802Innate Immune System
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