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MGP002519

Record overview

MGPD IDMGP002519
Gene ID5739
SpeciesHomo sapiens (Human)
Gene Nameprostaglandin I2 (prostacyclin) receptor (IP)
Gene Symbol PTGIR
SynonymsIP; PRIPR;
Alternate namesprostacyclin receptor; PGI receptor; PGI2 receptor; prostaglandin I2 receptor; prostanoid IP receptor;
Chromosome19
Map Location19q13.3
SummaryThe protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PTGIR

Proteins

prostacyclin receptor
Refseq ID:NP_000951
Protein GI:4506263
UniProt ID:P43119
mRNA ID:NM_000960
Length:386
RefSeq Status:
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMT
FFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIF
LCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
 
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