MGP Database

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MGP002579

Ontology/Pathway Information

Entrez Gene ID5906
Gene NameRAP1A, member of RAS oncogene family
Gene Symbol RAP1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030054 ISS:UniProtKBCcell junction
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005769 ISS:UniProtKBCearly endosome
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0032045 IEA:EnsemblCguanyl-nucleotide exchange factor complex
GO:0005770 ISS:UniProtKBClate endosome
GO:0043005 IEA:EnsemblCneuron projection
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0005886 TAS:ReactomeCplasma membrane
GO:0003924 TAS:ProtIncFGTPase activity
GO:0005525 IEA:UniProtKB-KWFGTP binding
GO:0032403 IDA:UniProtKBFprotein complex binding
GO:0008565 IDA:UniProtKBFprotein transporter activity
GO:0017034 ISS:UniProtKBFRap guanyl-nucleotide exchange factor activity
GO:0000186 TAS:ReactomePactivation of MAPKK activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0071320 IDA:UniProtKBPcellular response to cAMP
GO:1990090 ISS:UniProtKBPcellular response to nerve growth factor stimulus
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0061028 IMP:UniProtKBPestablishment of endothelial barrier
GO:2000301 IEA:EnsemblPnegative regulation of synaptic vesicle exocytosis
GO:0038180 ISS:UniProtKBPnerve growth factor signaling pathway
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0030168 TAS:ReactomePplatelet activation
GO:0070374 ISS:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0010976 ISS:UniProtKBPpositive regulation of neuron projection development
GO:0045860 ISS:UniProtKBPpositive regulation of protein kinase activity
GO:0032854 ISS:UniProtKBPpositive regulation of Rap GTPase activity
GO:2001214 ISS:UniProtKBPpositive regulation of vasculogenesis
GO:0015031 IDA:UniProtKBPprotein transport
GO:0032486 IMP:UniProtKBPRap protein signal transduction
GO:1901888 IMP:UniProtKBPregulation of cell junction assembly
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0007165 TAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_12002ARMS-mediated activation
REACT_12076Frs2-mediated activation
REACT_18274Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
REACT_15443GRB2:SOS provides linkage to MAPK signaling for Integrins
REACT_604Hemostasis
REACT_6900Immune System
REACT_1505Integration of energy metabolism
REACT_15523Integrin alphaIIb beta3 signaling
REACT_111217Metabolism
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_15381p130Cas linkage to MAPK signaling for integrins
REACT_798Platelet activation, signaling and aggregation
REACT_278Platelet Aggregation (Plug Formation)
REACT_12005Prolonged ERK activation events
REACT_23898Rap1 signalling
REACT_18325Regulation of insulin secretion
REACT_11061Signalling by NGF
REACT_12058Signalling to ERKs
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00320Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
SMP00321Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
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