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MGP002619

Record overview

MGPD IDMGP002619
Gene ID5997
SpeciesHomo sapiens (Human)
Gene Nameregulator of G-protein signaling 2
Gene Symbol RGS2
SynonymsG0S8;
Alternate namesregulator of G-protein signaling 2; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; regulator of G-protein signaling 2, 24kDa;
Chromosome1
Map Location1q31
SummaryRegulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [provided by RefSeq, Aug 2009]
OrthologsView orthologs and multiple alignments for RGS2

Proteins

regulator of G-protein signaling 2
Refseq ID:NP_002914
Protein GI:4506517
UniProt ID:P41220
mRNA ID:NM_002923
Length:211
RefSeq Status:
MQSAMFLAVQHDCRPMDKSAGSGHKSEEKREKMKRTLLKDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAF
LKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK
KPQITTEPHAT
 
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