MGP Database

MGP002619

Ontology/Pathway Information

Entrez Gene ID	5997
Gene Name	regulator of G-protein signaling 2
Gene Symbol	RGS2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IBA:GO_Central	C	cytoplasm
GO:0009898	ISS:BHF-UCL	C	cytoplasmic side of plasma membrane
GO:0005829	ISS:BHF-UCL	C	cytosol
GO:0005739	IEA:UniProtKB-SubCell	C	mitochondrion
GO:0043005	IEA:Ensembl	C	neuron projection
GO:0005730	IEA:UniProtKB-SubCell	C	nucleolus
GO:0005886	IBA:GO_Central	C	plasma membrane
GO:0005516	TAS:ProtInc	F	calmodulin binding
GO:0005096	IBA:GO_Central	F	GTPase activator activity
GO:0050873	IEA:Ensembl	P	brown fat cell differentiation
GO:0007049	IEA:UniProtKB-KW	P	cell cycle
GO:0043951	IEA:Ensembl	P	negative regulation of cAMP-mediated signaling
GO:0010614	ISS:BHF-UCL	P	negative regulation of cardiac muscle hypertrophy
GO:0045744	ISS:BHF-UCL	P	negative regulation of G-protein coupled receptor protein signaling pathway
GO:0043407	ISS:BHF-UCL	P	negative regulation of MAP kinase activity
GO:0010519	ISS:BHF-UCL	P	negative regulation of phospholipase activity
GO:0060452	ISS:BHF-UCL	P	positive regulation of cardiac muscle contraction
GO:0031116	IEA:Ensembl	P	positive regulation of microtubule polymerization
GO:0071877	ISS:BHF-UCL	P	regulation of adrenergic receptor signaling pathway
GO:0008277	TAS:ProtInc	P	regulation of G-protein coupled receptor protein signaling pathway
GO:0006417	IEA:UniProtKB-KW	P	regulation of translation
GO:0055119	ISS:BHF-UCL	P	relaxation of cardiac muscle
GO:0060087	IEA:Ensembl	P	relaxation of vascular smooth muscle
GO:0007283	IEA:Ensembl	P	spermatogenesis
GO:0038032	IEA:InterPro	P	termination of G-protein coupled receptor signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_18283	G alpha (q) signalling events
REACT_120966	Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184	GPCR downstream signaling
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction