MGP Database

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MGP002788

Ontology/Pathway Information

Entrez Gene ID6373
Gene Namechemokine (C-X-C motif) ligand 11
Gene Symbol CXCL11
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IBA:GO_CentralCextracellular space
GO:0008009 IDA:UniProtKBFchemokine activity
GO:0048248 IDA:UniProtKBFCXCR3 chemokine receptor binding
GO:0008201 IMP:UniProtKBFheparin binding
GO:0007267 TAS:ProtIncPcell-cell signaling
GO:0070098 IMP:UniProtKBPchemokine-mediated signaling pathway
GO:0006935 IDA:UniProtKBPchemotaxis
GO:0007186 IBA:GO_CentralPG-protein coupled receptor signaling pathway
GO:0006955 IBA:GO_CentralPimmune response
GO:0006954 TAS:ProtIncPinflammatory response
GO:0043950 IDA:UniProtKBPpositive regulation of cAMP-mediated signaling
GO:0030816 IDA:UniProtKBPpositive regulation of cAMP metabolic process
GO:0002690 IBA:GO_CentralPpositive regulation of leukocyte chemotaxis
GO:0051281 IDA:UniProtKBPpositive regulation of release of sequestered calcium ion into cytosol
GO:0042127 IMP:UniProtKBPregulation of cell proliferation
GO:0032496 IBA:GO_CentralPresponse to lipopolysaccharide
GO:0007165 TAS:ProtIncPsignal transduction
GO:0010818 IMP:UniProtKBPT cell chemotaxis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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