MGP Database

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MGP002832

Ontology/Pathway Information

Entrez Gene ID6480
Gene NameST6 beta-galactosamide alpha-2,6-sialyltranferase 1
Gene Symbol ST6GAL1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0032580 IEA:UniProtKB-SubCellCGolgi cisterna membrane
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0030173 IEA:InterProCintegral component of Golgi membrane
GO:0003835 IDA:UniProtKBFbeta-galactoside alpha-2,6-sialyltransferase activity
GO:0008373 IDA:UniProtKBFsialyltransferase activity
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0006959 TAS:ProtIncPhumoral immune response
GO:0006054 IDA:UniProtKBPN-acetylneuraminate metabolic process
GO:0016266 TAS:ReactomePO-glycan processing
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0018279 IDA:UniProtKBPprotein N-linked glycosylation via asparagine
GO:0097503 IDA:UniProtKBPsialylation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_22426Asparagine N-linked glycosylation
REACT_22433Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
REACT_268132Defective ALG11 causes ALG11-CDG (CDG-1p)
REACT_267773Defective ALG12 causes ALG12-CDG (CDG-1g)
REACT_268645Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
REACT_268144Defective ALG1 causes ALG1-CDG (CDG-1k)
REACT_268833Defective ALG2 causes ALG2-CDG (CDG-1i)
REACT_268185Defective ALG3 causes ALG3-CDG (CDG-1d)
REACT_267765Defective ALG6 causes ALG6-CDG (CDG-1c)
REACT_268459Defective ALG8 causes ALG8-CDG (CDG-1h)
REACT_268015Defective ALG9 causes ALG9-CDG (CDG-1l)
REACT_268438Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
REACT_268849Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
REACT_268813Defective MAN1B1 causes MRT15
REACT_268600Defective MGAT2 causes MGAT2-CDG (CDG-2a)
REACT_267905Defective MOGS causes MOGS-CDG (CDG-2b)
REACT_268619Defective MPDU1 causes MPDU1-CDG (CDG-1f)
REACT_268458Defective RFT1 causes RFT1-CDG (CDG-1n)
REACT_116125Disease
REACT_267875Diseases associated with N-glycosylation of proteins
REACT_268324Diseases of glycosylation
REACT_17015Metabolism of proteins
REACT_25085N-Glycan antennae elongation
REACT_25208N-glycan antennae elongation in the medial/trans-Golgi
REACT_263902O-linked glycosylation
REACT_115606O-linked glycosylation of mucins
REACT_22161Post-translational protein modification
REACT_264366Sialic acid metabolism
REACT_22387Synthesis of substrates in N-glycan biosythesis
REACT_115835Termination of O-glycan biosynthesis
REACT_25046Transport to the Golgi and subsequent modification
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