MGP Database

MGP003076

Record overview

MGPD IDMGP003076
Gene ID6915
SpeciesHomo sapiens (Human)
Gene Namethromboxane A2 receptor
Gene Symbol TBXA2R
SynonymsTXA2-R; BDPLT13;
Alternate namesthromboxane A2 receptor; prostanoid TP receptor;
Chromosome19
Map Location19p13.3
SummaryThis gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
OrthologsView orthologs and multiple alignments for TBXA2R

Proteins

thromboxane A2 receptor isoform alpha
Refseq ID:NP_001051
Protein GI:4507381
UniProt ID:P21731
mRNA ID:NM_001060
Length:343
RefSeq Status:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDP
GCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLF
SMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
 
thromboxane A2 receptor isoform beta
Refseq ID:NP_963998
Protein GI:260593681
UniProt ID:P21731
mRNA ID:NM_201636
Length:407
RefSeq Status:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDP
GCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLF
SMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNLRLPGSSDSRASASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTG
KALSRKD
 
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