MGP Database

MGP003076

Ontology/Pathway Information

Entrez Gene ID6915
Gene Namethromboxane A2 receptor
Gene Symbol TBXA2R
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0001669 IEA:EnsemblCacrosomal vesicle
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005085 TAS:ReactomeFguanyl-nucleotide exchange factor activity
GO:0004961 TAS:ProtIncFthromboxane A2 receptor activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0006954 IEA:EnsemblPinflammatory response
GO:0030168 TAS:ReactomePplatelet activation
GO:0045766 IEA:EnsemblPpositive regulation of angiogenesis
GO:0045777 IEA:EnsemblPpositive regulation of blood pressure
GO:0007204 IEA:EnsemblPpositive regulation of cytosolic calcium ion concentration
GO:0043547 TAS:GOCPpositive regulation of GTPase activity
GO:0045987 IEA:EnsemblPpositive regulation of smooth muscle contraction
GO:0045907 IEA:EnsemblPpositive regulation of vasoconstriction
GO:0042493 IEA:EnsemblPresponse to drug
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0019932 IEA:EnsemblPsecond-messenger-mediated signaling
GO:0038193 TAS:GOCPthromboxane A2 signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_18352Eicosanoid ligand-binding receptors
REACT_18407G alpha (12/13) signalling events
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_604Hemostasis
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_798Platelet activation, signaling and aggregation
REACT_18425Prostanoid ligand receptors
REACT_20524Signal amplification
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_20647Thromboxane signalling through TP receptor
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