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MGP Database

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MGP003179

Ontology/Pathway Information

Entrez Gene ID	7166
Gene Name	tryptophan hydroxylase 1
Gene Symbol	TPH1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	TAS:Reactome	C	cytosol
GO:0043005	IEA:Ensembl	C	neuron projection
GO:0016597	IEA:InterPro	F	amino acid binding
GO:0005506	IEA:InterPro	F	iron ion binding
GO:0004510	IEA:UniProtKB-EC	F	tryptophan 5-monooxygenase activity
GO:0009072	IEA:InterPro	P	aromatic amino acid family metabolic process
GO:0046849	IEA:Ensembl	P	bone remodeling
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0007623	IEA:Ensembl	P	circadian rhythm
GO:0046219	TAS:Reactome	P	indolalkylamine biosynthetic process
GO:0060749	IEA:Ensembl	P	mammary gland alveolus development
GO:0030279	IEA:Ensembl	P	negative regulation of ossification
GO:0035902	IEA:Ensembl	P	response to immobilization stress
GO:0042427	IEA:UniProtKB-UniPathway	P	serotonin biosynthetic process
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_15513	Amine-derived hormones
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives
REACT_15439	Serotonin and melatonin biosynthesis

SMP Pathway Links

SMP ID	Description
SMP00063	Tryptophan Metabolism