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MGP003226

Record overview

MGPD IDMGP003226
Gene ID7295
SpeciesHomo sapiens (Human)
Gene Namethioredoxin
Gene Symbol TXN
SynonymsTRX; TRDX; TRX1;
Alternate namesthioredoxin; ADF; ATL-derived factor; SASP; TXN delta 3; surface-associated sulphydryl protein; thioredoxin delta 3;
Chromosome9
Map Location9q31
SummaryThe protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
OrthologsView orthologs and multiple alignments for TXN

Proteins

thioredoxin isoform 1
Refseq ID:NP_003320
Protein GI:50592994
UniProt ID:P10599
mRNA ID:NM_003329
Length:105
RefSeq Status:
MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEAT
INELV
 
thioredoxin isoform 2
Refseq ID:NP_001231867
Protein GI:349732256
UniProt ID:P10599
mRNA ID:NM_001244938
Length:85
RefSeq Status:
MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
 
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