MGP Database

MGP003258

Ontology/Pathway Information

Entrez Gene ID	7351
Gene Name	uncoupling protein 2 (mitochondrial, proton carrier)
Gene Symbol	UCP2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005743	TAS:Reactome	C	mitochondrial inner membrane
GO:0007568	IEA:Ensembl	P	aging
GO:0044237	TAS:Reactome	P	cellular metabolic process
GO:0034198	IEA:Ensembl	P	cellular response to amino acid starvation
GO:0071333	IEA:Ensembl	P	cellular response to glucose stimulus
GO:0032869	IEA:Ensembl	P	cellular response to insulin stimulus
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0097421	IEA:Ensembl	P	liver regeneration
GO:0006839	IEA:Ensembl	P	mitochondrial transport
GO:0043066	IEA:Ensembl	P	negative regulation of apoptotic process
GO:0061179	IEA:Ensembl	P	negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0010942	IEA:Ensembl	P	positive regulation of cell death
GO:0015992	TAS:Reactome	P	proton transport
GO:0051881	IEA:Ensembl	P	regulation of mitochondrial membrane potential
GO:0022904	TAS:Reactome	P	respiratory electron transport chain
GO:0070542	IEA:Ensembl	P	response to fatty acid
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0000303	IEA:Ensembl	P	response to superoxide
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006810	NAS:ProtInc	P	transport

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111217	Metabolism
REACT_6341	Mitochondrial Uncoupling Proteins
REACT_6305	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_111083	The citric acid (TCA) cycle and respiratory electron transport
REACT_6258	The fatty acid cycling model
REACT_6196	The proton buffering model