MGP Database

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MGP003338

Ontology/Pathway Information

Entrez Gene ID7531
Gene Nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
Gene Symbol YWHAE
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 IEA:EnsemblCaxon
GO:0030659 TAS:ReactomeCcytoplasmic vesicle membrane
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005871 IEA:EnsemblCkinesin complex
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0042826 IPI:BHF-UCLFhistone deacetylase binding
GO:0044325 IPI:BHF-UCLFion channel binding
GO:0023026 IDA:UniProtKBFMHC class II protein complex binding
GO:0051219 IPI:BHF-UCLFphosphoprotein binding
GO:0050815 IPI:BHF-UCLFphosphoserine binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0015459 IDA:BHF-UCLFpotassium channel regulator activity
GO:0046982 IPI:BHF-UCLFprotein heterodimerization activity
GO:0006915 TAS:ReactomePapoptotic process
GO:0097190 TAS:ReactomePapoptotic signaling pathway
GO:0021987 IEA:EnsemblPcerebral cortex development
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0021766 IEA:EnsemblPhippocampus development
GO:0035329 TAS:ReactomePhippo signaling
GO:0035556 TAS:ProtIncPintracellular signal transduction
GO:0097193 TAS:ReactomePintrinsic apoptotic signaling pathway
GO:0061024 TAS:ReactomePmembrane organization
GO:0086013 IC:BHF-UCLPmembrane repolarization during cardiac muscle cell action potential
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:1902309 IDA:BHF-UCLPnegative regulation of peptidyl-serine dephosphorylation
GO:0001764 IEA:EnsemblPneuron migration
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:1900740 TAS:ReactomePpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0006605 IEA:EnsemblPprotein targeting
GO:0043281 TAS:ReactomePregulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0086091 IC:BHF-UCLPregulation of heart rate by cardiac conduction
GO:0003064 NAS:BHF-UCLPregulation of heart rate by hormone
GO:0060306 IDA:BHF-UCLPregulation of membrane repolarization
GO:1901016 IDA:BHF-UCLPregulation of potassium ion transmembrane transporter activity
GO:0021762 IEP:UniProtKBPsubstantia nigra development
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_549Activation of BAD and translocation to mitochondria
REACT_697Activation of BH3-only proteins
REACT_267965Anchoring of the basal body to the plasma membrane
REACT_578Apoptosis
REACT_268265Assembly of the primary cilium
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_13720Cell death signalling via NRAGE, NRIF and NADE
REACT_120956Cellular responses to stress
REACT_263897Cellular response to heat stress
REACT_15479Centrosome maturation
REACT_2203G2/M Transition
REACT_264071HSF1 activation
REACT_964Intrinsic Pathway for Apoptosis
REACT_15364Loss of Nlp from mitotic centrosomes
REACT_15451Loss of proteins required for interphase microtubule organization from the centrosome
REACT_11123Membrane Trafficking
REACT_21391Mitotic G2-G2/M phases
REACT_13526NADE modulates death signalling
REACT_264135Organelle biogenesis and maintenance
REACT_13776p75 NTR receptor-mediated signalling
REACT_268456Programmed Cell Death
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_264487Regulation of HSF1-mediated heat shock response
REACT_160315Regulation of PLK1 Activity at G2/M Transition
REACT_118607Signaling by Hippo
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_147867Translocation of GLUT4 to the plasma membrane
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