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MGP003340

Record overview

MGPD IDMGP003340
Gene ID7533
SpeciesHomo sapiens (Human)
Gene Nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
Gene Symbol YWHAH
SynonymsYWHA1;
Alternate names14-3-3 protein eta; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide;
Chromosome22
Map Location22q12.3
SummaryThis gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
OrthologsView orthologs and multiple alignments for YWHAH

Proteins

14-3-3 protein eta
Refseq ID:NP_003396
Protein GI:4507951
UniProt ID:Q04917
mRNA ID:NM_003405
Length:246
RefSeq Status:
MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDV
LSLLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQA
FDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN
 
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