MGP Database

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MGP003340

Ontology/Pathway Information

Entrez Gene ID7533
Gene Nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
Gene Symbol YWHAH
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0030659 TAS:ReactomeCcytoplasmic vesicle membrane
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0014704 IC:BHF-UCLCintercalated disc
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0019899 IPI:BHF-UCLFenzyme binding
GO:0035259 IPI:UniProtKBFglucocorticoid receptor binding
GO:0005159 ISS:UniProtKBFinsulin-like growth factor receptor binding
GO:0044325 IPI:BHF-UCLFion channel binding
GO:0019904 ISS:UniProtKBFprotein domain specific binding
GO:0046982 IPI:BHF-UCLFprotein heterodimerization activity
GO:0017080 IDA:BHF-UCLFsodium channel regulator activity
GO:0006915 TAS:ReactomePapoptotic process
GO:0006713 IDA:UniProtKBPglucocorticoid catabolic process
GO:0042921 IDA:UniProtKBPglucocorticoid receptor signaling pathway
GO:0006886 ISS:UniProtKBPintracellular protein transport
GO:0097193 TAS:ReactomePintrinsic apoptotic signaling pathway
GO:0086010 IDA:BHF-UCLPmembrane depolarization during action potential
GO:0061024 TAS:ReactomePmembrane organization
GO:0050774 ISS:UniProtKBPnegative regulation of dendrite morphogenesis
GO:1900740 TAS:ReactomePpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0045893 IDA:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045664 ISS:UniProtKBPregulation of neuron differentiation
GO:2000649 IDA:BHF-UCLPregulation of sodium ion transmembrane transporter activity
GO:0002028 IDA:BHF-UCLPregulation of sodium ion transport
GO:0048167 ISS:UniProtKBPregulation of synaptic plasticity
GO:0021762 IEP:UniProtKBPsubstantia nigra development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_549Activation of BAD and translocation to mitochondria
REACT_697Activation of BH3-only proteins
REACT_578Apoptosis
REACT_964Intrinsic Pathway for Apoptosis
REACT_11123Membrane Trafficking
REACT_268456Programmed Cell Death
REACT_147867Translocation of GLUT4 to the plasma membrane
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