MGP Database

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MGP003712

Ontology/Pathway Information

Entrez Gene ID8835
Gene Namesuppressor of cytokine signaling 2
Gene Symbol SOCS2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 NAS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005131 NAS:UniProtKBFgrowth hormone receptor binding
GO:0005159 IPI:UniProtKBFinsulin-like growth factor receptor binding
GO:0008269 TAS:ProtIncFJAK pathway signal transduction adaptor activity
GO:0004860 IBA:GO_CentralFprotein kinase inhibitor activity
GO:0005070 TAS:ProtIncFSH3/SH2 adaptor activity
GO:0032870 IDA:BHF-UCLPcellular response to hormone stimulus
GO:0019221 IBA:GO_CentralPcytokine-mediated signaling pathway
GO:0060396 IDA:BHF-UCLPgrowth hormone receptor signaling pathway
GO:0007259 TAS:ProtIncPJAK-STAT cascade
GO:0060397 TAS:ReactomePJAK-STAT cascade involved in growth hormone signaling pathway
GO:0043066 TAS:ProtIncPnegative regulation of apoptotic process
GO:0046627 IBA:GO_CentralPnegative regulation of insulin receptor signaling pathway
GO:0046426 IBA:GO_CentralPnegative regulation of JAK-STAT cascade
GO:0006469 IBA:GO_CentralPnegative regulation of protein kinase activity
GO:0009967 TAS:GOCPpositive regulation of signal transduction
GO:0016567 IEA:UniProtKB-UniPathwayPprotein ubiquitination
GO:0001558 NAS:UniProtKBPregulation of cell growth
GO:0009966 NAS:UniProtKBPregulation of signal transduction
GO:0032355 IDA:BHF-UCLPresponse to estradiol
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_111133Growth hormone receptor signaling
REACT_6900Immune System
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