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MGP003906

Record overview

MGPD IDMGP003906
Gene ID9446
SpeciesHomo sapiens (Human)
Gene Nameglutathione S-transferase omega 1
Gene Symbol GSTO1
SynonymsP28; SPG-R; GSTO 1-1; GSTTLp28; HEL-S-21;
Alternate namesglutathione S-transferase omega-1; GSTO-1; MMA(V) reductase; S-(Phenacyl)glutathione reductase; epididymis secretory protein Li 21; glutathione S-transferase omega 1-1; glutathione-S-transferase like; glutathione-dependent dehydroascorbate reductase; monomethylarsonic acid reductase;
Chromosome10
Map Location10q25.1
EC Number2.5.1.18
SummaryThe protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
OrthologsView orthologs and multiple alignments for GSTO1

Proteins

glutathione S-transferase omega-1 isoform 1
Refseq ID:NP_004823
Protein GI:4758484
UniProt ID:P78417
mRNA ID:NM_004832
Length:241
RefSeq Status:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGK
KLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLK
LWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
 
glutathione S-transferase omega-1 isoform 2
Refseq ID:NP_001177931
Protein GI:300360532
UniProt ID:P78417
mRNA ID:NM_001191002
Length:208
RefSeq Status:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGK
KLLPDDPYEKACQKMILELFSKVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNS
PEACDYGL
 
glutathione S-transferase omega-1 isoform 3
Refseq ID:NP_001177932
Protein GI:300360534
UniProt ID:P78417
mRNA ID:NM_001191003
Length:213
RefSeq Status:
MRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVG
SFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLEL
YLQNSPEACDYGL
 
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