MGP Database

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MGP003906

Ontology/Pathway Information

Entrez Gene ID9446
Gene Nameglutathione S-transferase omega 1
Gene Symbol GSTO1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0045174 IDA:UniProtKBFglutathione dehydrogenase (ascorbate) activity
GO:0004364 IDA:UniProtKBFglutathione transferase activity
GO:0050610 IEA:UniProtKB-ECFmethylarsonate reductase activity
GO:0016491 IDA:UniProtKBFoxidoreductase activity
GO:0071243 IDA:UniProtKBPcellular response to arsenic-containing substance
GO:1901687 TAS:ReactomePglutathione derivative biosynthetic process
GO:0019852 IDA:UniProtKBPL-ascorbic acid metabolic process
GO:0060315 IDA:BHF-UCLPnegative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 IDA:BHF-UCLPpositive regulation of ryanodine-sensitive calcium-release channel activity
GO:0014810 IC:BHF-UCLPpositive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0010881 IC:BHF-UCLPregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010880 IDA:BHF-UCLPregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0042178 IDA:UniProtKBPxenobiotic catabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
REACT_6959Phase II conjugation
REACT_11202Vitamin C (ascorbate) metabolism
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