MGP Database

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MGP003941

Ontology/Pathway Information

Entrez Gene ID9536
Gene Nameprostaglandin E synthase
Gene Symbol PTGES
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 IDA:UniProtKBCintegral component of membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0005641 IEA:EnsemblCnuclear envelope lumen
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0043295 IDA:UniProtKBFglutathione binding
GO:0050220 IDA:UniProtKBFprostaglandin-E synthase activity
GO:0002526 IEA:EnsemblPacute inflammatory response
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0002544 IEA:EnsemblPchronic inflammatory response
GO:0019371 TAS:ReactomePcyclooxygenase pathway
GO:0008285 IEA:EnsemblPnegative regulation of cell proliferation
GO:0001516 IDA:UniProtKBPprostaglandin biosynthetic process
GO:0006693 TAS:ProtIncPprostaglandin metabolic process
GO:0051592 IEA:EnsemblPresponse to calcium ion
GO:0034097 IEA:EnsemblPresponse to cytokine
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
GO:0032526 IEA:EnsemblPresponse to retinoic acid
GO:0007165 NAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_150149Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
SMP Pathway Links
SMP IDDescription
SMP00710Acetaminophen Action Pathway
SMP00083Acetylsalicylic Acid Action Pathway
SMP00692Antipyrine Action Pathway
SMP00693Antrafenine Action Pathway
SMP00075Arachidonic Acid Metabolism
SMP00102Bromfenac Action Pathway
SMP00694Carprofen Action Pathway
SMP00096Celecoxib Action Pathway
SMP00093Diclofenac Action Pathway
SMP00289Diflunisal Action Pathway
SMP00084Etodolac Action Pathway
SMP00695Etoricoxib Action Pathway
SMP00696Fenoprofen Action Pathway
SMP00697Flurbiprofen Action Pathway
SMP00086Ibuprofen Action Pathway
SMP00104Indomethacin Action Pathway
SMP00085Ketoprofen Action Pathway
SMP00098Ketorolac Action Pathway
SMP00353Leukotriene C4 Synthesis Deficiency
SMP00700Lornoxicam Action Pathway
SMP00699Lumiracoxib Action Pathway
SMP00698Magnesium salicylate Action Pathway
SMP00109Mefenamic Acid Action Pathway
SMP00106Meloxicam Action Pathway
SMP00114Nabumetone Action Pathway
SMP00120Naproxen Action Pathway
SMP00702Nepafenac Action Pathway
SMP00113Oxaprozin Action Pathway
SMP00701Phenylbutazone Action Pathway
SMP00077Piroxicam Action Pathway
SMP00087Rofecoxib Action Pathway
SMP00708Salicylate-sodium Action Pathway
SMP00709Salicylic Acid Action Pathway
SMP00707Salsalate Action Pathway
SMP00094Sulindac Action Pathway
SMP00101Suprofen Action Pathway
SMP00706Tenoxicam Action Pathway
SMP00705Tiaprofenic Acid Action Pathway
SMP00704Tolmetin Action Pathway
SMP00703Trisalicylate-choline Action Pathway
SMP00116Valdecoxib Action Pathway
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