MGP Database

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MGP004297

Ontology/Pathway Information

Entrez Gene ID10588
Gene Name5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
Gene Symbol MTHFS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0030272 IDA:UniProtKBF5-formyltetrahydrofolate cyclo-ligase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005542 IEA:UniProtKB-KWFfolic acid binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0015942 NAS:UniProtKBPformate metabolic process
GO:0046653 IDA:UniProtKBPtetrahydrofolate metabolic process
SMP Pathway Links
SMP IDDescription
SMP00724Folate malabsorption, hereditary
SMP00053Folate Metabolism
SMP00543Homocystinuria due to defect of N(5,10)-methylene THF deficiency
SMP00432Methotrexate Action Pathway
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