MGP Database

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MGP004479

Ontology/Pathway Information

Entrez Gene ID11197
Gene NameWNT inhibitory factor 1
Gene Symbol WIF1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0007275 IEA:UniProtKB-KWPmulticellular organismal development
GO:0045600 IEA:EnsemblPpositive regulation of fat cell differentiation
GO:0007165 NAS:ProtIncPsignal transduction
GO:0016055 IEA:UniProtKB-KWPWnt signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_264594misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
REACT_264383negative regulation of TCF-dependent signaling by WNT ligand antagonists
REACT_264378RNF mutants show enhanced WNT signaling and proliferation
REACT_11045Signaling by Wnt
REACT_264125Signaling by WNT in cancer
REACT_111102Signal Transduction
REACT_264596TCF dependent signaling in response to WNT
REACT_264356XAV939 inhibits tankyrase, stabilizing AXIN
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