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MGP004479

UniProt Annotations

Entry Information
Gene NameWNT inhibitory factor 1
Protein EntryWIF1_HUMAN
UniProt IDQ9Y5W5
SpeciesHuman
Comments
Comment typeDescription
FunctionBinds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
InteractionP27467:Wnt3a (xeno); NbExp=7; IntAct=EBI-3922719, EBI-2899665; P22725:Wnt5a (xeno); NbExp=7; IntAct=EBI-3922719, EBI-1570983;
SimilarityContains 1 WIF domain. {ECO:0000255|PROSITE- ProRule:PRU00222}.
SimilarityContains 5 EGF-like domains. {ECO:0000255|PROSITE- ProRule:PRU00076}.
Subcellular LocationSecreted.
SubunitInteracts with MYOC. {ECO:0000269|PubMed:19188438}.
Web ResourceName=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/WIF1ID44085ch12q14.html";
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