MGP Database

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MGP004514

Ontology/Pathway Information

Entrez Gene ID11343
Gene Namemonoglyceride lipase
Gene Symbol MGLL
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0005654 IDA:HPACnucleoplasm
GO:0005886 TAS:ReactomeCplasma membrane
GO:0045202 IEA:EnsemblCsynapse
GO:0047372 ISS:UniProtKBFacylglycerol lipase activity
GO:0008289 IEA:EnsemblFlipid binding
GO:0004622 TAS:ProtIncFlysophospholipase activity
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0036155 TAS:ReactomePacylglycerol acyl-chain remodeling
GO:0046464 ISS:UniProtKBPacylglycerol catabolic process
GO:0019369 ISS:UniProtKBParachidonic acid metabolic process
GO:0007596 TAS:ReactomePblood coagulation
GO:0006633 IEA:UniProtKB-KWPfatty acid biosynthetic process
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0006954 TAS:ProtIncPinflammatory response
GO:0006629 TAS:ProtIncPlipid metabolic process
GO:0060292 IEA:EnsemblPlong term synaptic depression
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0030168 TAS:ReactomePplatelet activation
GO:2000124 ISS:UniProtKBPregulation of endocannabinoid signaling pathway
GO:0050727 ISS:UniProtKBPregulation of inflammatory response
GO:0051930 ISS:UniProtKBPregulation of sensory perception of pain
GO:0009966 ISS:UniProtKBPregulation of signal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0019433 TAS:ReactomePtriglyceride catabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121122Acyl chain remodeling of DAG and TAG
REACT_19308Arachidonate production from DAG
REACT_2202Effects of PIP2 hydrolysis
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_121401Glycerophospholipid biosynthesis
REACT_19184GPCR downstream signaling
REACT_604Hemostasis
REACT_494Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
REACT_602Lipid digestion, mobilization, and transport
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_798Platelet activation, signaling and aggregation
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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