MGP Database

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MGP004761

Ontology/Pathway Information

Entrez Gene ID25805
Gene NameBMP and activin membrane-bound inhibitor
Gene Symbol BAMBI
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0005109 IPI:BHF-UCLFfrizzled binding
GO:0005114 TAS:BHF-UCLFtype II transforming growth factor beta receptor binding
GO:0016477 IDA:BHF-UCLPcell migration
GO:0030512 IDA:BHF-UCLPnegative regulation of transforming growth factor beta receptor signaling pathway
GO:0090263 IDA:BHF-UCLPpositive regulation of canonical Wnt signaling pathway
GO:0035413 IMP:BHF-UCLPpositive regulation of catenin import into nucleus
GO:0008284 IMP:BHF-UCLPpositive regulation of cell proliferation
GO:0010718 IMP:BHF-UCLPpositive regulation of epithelial to mesenchymal transition
GO:0032092 IMP:BHF-UCLPpositive regulation of protein binding
GO:0045893 IDA:BHF-UCLPpositive regulation of transcription, DNA-templated
GO:0008360 IMP:BHF-UCLPregulation of cell shape
GO:0007179 TAS:ReactomePtransforming growth factor beta receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_120727Downregulation of TGF-beta receptor signaling
REACT_169398Loss of Function of SMAD2/3 in Cancer
REACT_169219Loss of Function of SMAD4 in Cancer
REACT_169311Loss of Function of TGFBR1 in Cancer
REACT_169435Loss of Function of TGFBR2 in Cancer
REACT_6844Signaling by TGF-beta Receptor Complex
REACT_169122Signaling by TGF-beta Receptor Complex in Cancer
REACT_111102Signal Transduction
REACT_169165SMAD2/3 MH2 Domain Mutants in Cancer
REACT_169103SMAD2/3 Phosphorylation Motif Mutants in Cancer
REACT_169107SMAD4 MH2 Domain Mutants in Cancer
REACT_120850TGF-beta receptor signaling activates SMADs
REACT_169263TGFBR1 KD Mutants in Cancer
REACT_169445TGFBR1 LBD Mutants in Cancer
REACT_169440TGFBR2 Kinase Domain Mutants in Cancer
REACT_169192TGFBR2 MSI Frameshift Mutants in Cancer
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