Summary of Study ST001848
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001165. The data can be accessed directly via it's Project DOI: 10.21228/M8411V This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001848 |
| Study Title | Untargeted mass spectrometry reveals impact of high fat diet on peripheral amino acid regulation in a mouse model of Alzheimer’s Disease |
| Study Type | untargeted metabolomics analysis |
| Study Summary | APPSwe/PS1ΔE9 (APP/PSEN1) transgenic mice (to represent familial or early-onset AD) and wild-type litter mater controls were fed either a high-fat diet (HFD, 60% kcal from lard), low-fat diet (LFD, 10% kcal from lard) from 2 months of age, or reversal diet (REV, high-fat followed by low-fat from 9.5 months). |
| Institute | Vanderbilt University |
| Department | Chemistry |
| Laboratory | Center for Innovative Technology |
| Last Name | Codreanu |
| First Name | Simona |
| Address | 3009, Liberty Hills Drive |
| SIMONA.CODREANU@VANDERBILT.EDU | |
| Phone | 6153477458 |
| Submit Date | 2021-06-03 |
| Num Groups | 6 |
| Total Subjects | 36 |
| Num Males | 18 |
| Num Females | 18 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-08-31 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | gender |
|---|---|---|
| SA171968 | S29 | F | genotype:APP | treatment:HFD |
| SA171969 | S30 | F | genotype:APP | treatment:HFD |
| SA171970 | S28 | F | genotype:APP | treatment:HFD |
| SA171971 | S24 | F | genotype:APP | treatment:LFD |
| SA171972 | S23 | F | genotype:APP | treatment:LFD |
| SA171973 | S22 | F | genotype:APP | treatment:LFD |
| SA171974 | S34 | F | genotype:APP | treatment:REV |
| SA171975 | S36 | F | genotype:APP | treatment:REV |
| SA171976 | S35 | F | genotype:APP | treatment:REV |
| SA171977 | S26 | F | genotype:WT | treatment:HFD |
| SA171978 | S25 | F | genotype:WT | treatment:HFD |
| SA171979 | S27 | F | genotype:WT | treatment:HFD |
| SA171980 | S21 | F | genotype:WT | treatment:LFD |
| SA171981 | S20 | F | genotype:WT | treatment:LFD |
| SA171982 | S19 | F | genotype:WT | treatment:LFD |
| SA171983 | S31 | F | genotype:WT | treatment:REV |
| SA171984 | S32 | F | genotype:WT | treatment:REV |
| SA171985 | S33 | F | genotype:WT | treatment:REV |
| SA171986 | S10 | M | genotype:APP | treatment:HFD |
| SA171987 | S11 | M | genotype:APP | treatment:HFD |
| SA171988 | S12 | M | genotype:APP | treatment:HFD |
| SA171989 | S05 | M | genotype:APP | treatment:LFD |
| SA171990 | S04 | M | genotype:APP | treatment:LFD |
| SA171991 | S06 | M | genotype:APP | treatment:LFD |
| SA171992 | S18 | M | genotype:APP | treatment:REV |
| SA171993 | S17 | M | genotype:APP | treatment:REV |
| SA171994 | S16 | M | genotype:APP | treatment:REV |
| SA171995 | S09 | M | genotype:WT | treatment:HFD |
| SA171996 | S07 | M | genotype:WT | treatment:HFD |
| SA171997 | S08 | M | genotype:WT | treatment:HFD |
| SA171998 | S03 | M | genotype:WT | treatment:LFD |
| SA171999 | S02 | M | genotype:WT | treatment:LFD |
| SA172000 | S01 | M | genotype:WT | treatment:LFD |
| SA172001 | S14 | M | genotype:WT | treatment:REV |
| SA172002 | S13 | M | genotype:WT | treatment:REV |
| SA172003 | S15 | M | genotype:WT | treatment:REV |
| Showing results 1 to 36 of 36 |
