Summary of Study ST001848

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001165. The data can be accessed directly via it's Project DOI: 10.21228/M8411V This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001848
Study TitleUntargeted mass spectrometry reveals impact of high fat diet on peripheral amino acid regulation in a mouse model of Alzheimer’s Disease
Study Typeuntargeted metabolomics analysis
Study SummaryAPPSwe/PS1ΔE9 (APP/PSEN1) transgenic mice (to represent familial or early-onset AD) and wild-type litter mater controls were fed either a high-fat diet (HFD, 60% kcal from lard), low-fat diet (LFD, 10% kcal from lard) from 2 months of age, or reversal diet (REV, high-fat followed by low-fat from 9.5 months).
Institute
Vanderbilt University
DepartmentChemistry
LaboratoryCenter for Innovative Technology
Last NameCodreanu
First NameSimona
Address3009, Liberty Hills Drive
EmailSIMONA.CODREANU@VANDERBILT.EDU
Phone6153477458
Submit Date2021-06-03
Num Groups6
Total Subjects36
Num Males18
Num Females18
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2021-08-31
Release Version1
Simona Codreanu Simona Codreanu
https://dx.doi.org/10.21228/M8411V
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id gender genotype treatment
SA171968S29F APP HFD
SA171969S30F APP HFD
SA171970S28F APP HFD
SA171971S24F APP LFD
SA171972S23F APP LFD
SA171973S22F APP LFD
SA171974S34F APP REV
SA171975S36F APP REV
SA171976S35F APP REV
SA171977S26F WT HFD
SA171978S25F WT HFD
SA171979S27F WT HFD
SA171980S21F WT LFD
SA171981S20F WT LFD
SA171982S19F WT LFD
SA171983S31F WT REV
SA171984S32F WT REV
SA171985S33F WT REV
SA171986S10M APP HFD
SA171987S11M APP HFD
SA171988S12M APP HFD
SA171989S05M APP LFD
SA171990S04M APP LFD
SA171991S06M APP LFD
SA171992S18M APP REV
SA171993S17M APP REV
SA171994S16M APP REV
SA171995S09M WT HFD
SA171996S07M WT HFD
SA171997S08M WT HFD
SA171998S03M WT LFD
SA171999S02M WT LFD
SA172000S01M WT LFD
SA172001S14M WT REV
SA172002S13M WT REV
SA172003S15M WT REV
Showing results 1 to 36 of 36
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