Summary of Study ST000881
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000611. The data can be accessed directly via it's Project DOI: 10.21228/M8XQ41 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000881 |
| Study Title | Targeted metabolomics data of leprosy patients with type 1 reaction |
| Study Type | Targeted MS/MS analysis in retrospective serum samples of leprosy patients with type 1 reaction |
| Study Summary | Targeted metabolomics-based analyses of pooled sera from 7 patients with T1R were conducted via LC-MS/MS. |
| Institute | Colorado State University |
| Department | Department of Microbiology, Immunology, and Pathology |
| Laboratory | Belisle |
| Last Name | Silva |
| First Name | Carlos |
| Address | Rampart Road, 1682 Campus Delivery |
| cadriano@rams.colostate.edu | |
| Phone | 9702154962 |
| Submit Date | 2017-08-02 |
| Num Groups | 2 |
| Total Subjects | 16 |
| Num Males | 5 |
| Num Females | 11 |
| Study Comments | 2 groups (first group was leprosy patients with type 1 reaction, N=9; and second group was leprosy patients without type 1 reaction, N=7) 5 males (3 were leprosy patients with type 1 reaction and 2 were leprosy patients without type 1 reaction), 11 females (4 were leprosy patients with type 1 reaction and 7 were leprosy patients without type 1 reaction). For this study we used retrospective sera samples. |
| Publications | J Infect Dis. 2017 Feb 1;215(3):431-439. doi: 10.1093/infdis/jiw541. |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2017-08-02 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN001437 |
|---|---|
| Analysis type | MS |
| Chromatography type | Reversed phase |
| Chromatography system | Agilent 1290 |
| Column | Waters Xbridge BEH C18 XP (100 x 2.1mm,2.5um) |
| MS Type | ESI |
| MS instrument type | QTOF |
| MS instrument name | Agilent 6510 QTOF |
| Ion Mode | NEGATIVE |
| Units | arbitrary units |
Chromatography:
| Chromatography ID: | CH001008 |
| Chromatography Summary: | This analysis was performed only on negative mode. The solvent gradient used for all chromatography was 2% solvent B for 3 min followed by a 15 min linear gradient of 2% to 98% solvent B, which was held for 0.3 min. Then returned to starting conditions over 1.2 min. |
| Instrument Name: | Agilent 1290 |
| Column Name: | Waters Xbridge BEH C18 XP (100 x 2.1mm,2.5um) |
| Column Temperature: | 50C |
| Flow Gradient: | 0.25 mL/min |
| Flow Rate: | 0.25 mL/min |
| Injection Temperature: | 4C |
| Sample Injection: | 20uL |
| Solvent A: | 89% water/5% acetonitrile/5% isopropanol; 5 mM ammonium acetate |
| Solvent B: | 50% acetonitrile/50% isopropanol; 5 mM ammonium acetate |
| Capillary Voltage: | 2.8 kV |
| Chromatography Type: | Reversed phase |
