Summary of Study ST000881

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000611. The data can be accessed directly via it's Project DOI: 10.21228/M8XQ41 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000881
Study TitleTargeted metabolomics data of leprosy patients with type 1 reaction
Study TypeTargeted MS/MS analysis in retrospective serum samples of leprosy patients with type 1 reaction
Study SummaryTargeted metabolomics-based analyses of pooled sera from 7 patients with T1R were conducted via LC-MS/MS.
Institute
Colorado State University
DepartmentDepartment of Microbiology, Immunology, and Pathology
LaboratoryBelisle
Last NameSilva
First NameCarlos
AddressRampart Road, 1682 Campus Delivery
Emailcadriano@rams.colostate.edu
Phone9702154962
Submit Date2017-08-02
Num Groups2
Total Subjects16
Num Males5
Num Females11
Study Comments2 groups (first group was leprosy patients with type 1 reaction, N=9; and second group was leprosy patients without type 1 reaction, N=7) 5 males (3 were leprosy patients with type 1 reaction and 2 were leprosy patients without type 1 reaction), 11 females (4 were leprosy patients with type 1 reaction and 7 were leprosy patients without type 1 reaction). For this study we used retrospective sera samples.
PublicationsJ Infect Dis. 2017 Feb 1;215(3):431-439. doi: 10.1093/infdis/jiw541.
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-08-02
Release Version1
Carlos Silva Carlos Silva
https://dx.doi.org/10.21228/M8XQ41
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Collection:

Collection ID:CO000909
Collection Summary:The whole blood (10 mL) was collected in a Vacutainer tube from Becton Dickinson (BD). After collection of the whole blood, it was allowed the blood to clot by leaving it undisturbed at room temperature for 30 minutes. The clot was removed by centrifuging at 1,000–2,000 x g for 10 minutes in a refrigerated centrifuge (4 C). The resulting supernatant is designated serum. The serum samples were aliquoted in 100 microliters and stored in a serum bank at -80C. These samples were collected in the Leprosy Outpatient Unit (Oswaldo Cruz Foundation, Rio de Janeiro, Brazil) and then they were sent in dry ice to Colorado State University, where it was processed and analyzed for metabolomics. At Colorado State University the samples were stored at -80C until processing.
Sample Type:Serum
Collection Location:Leprosy Outpatient Unit (Oswaldo Cruz Foundation, Rio de Janeiro, Brazil)
Collection Duration:30 minutes
Storage Conditions:-80C
Additives:no
Blood Serum Or Plasma:Serum
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