Summary of Study ST000104
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000096. The data can be accessed directly via it's Project DOI: 10.21228/M8NK5J This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000104 |
Study Title | Factors for Epigenetic Silencing of Lung Cancer Genes |
Study Type | Metabolomic analysis of Plasma |
Study Summary | To test the hypothesis that the propensity for silencing of tumor suppressor genes in the respiratory epithelium of chronic smokers by promoter hypermethylation is influenced by sequence variations that modify the activity of genes and microRNAĆs that directly or indirectly influence de novo methylation and chromatin remodeling. |
Institute | University of North Carolina |
Department | Discovery Science Technology |
Laboratory | Sumner Lab |
Last Name | Sumner |
First Name | Susan |
Address | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
susan_sumner @unc.edu | |
Phone | 704-250-5066 |
Submit Date | 2014-09-29 |
Num Groups | 3 |
Total Subjects | 69 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Uploaded File Size | 36 M |
Analysis Type Detail | NMR |
Release Date | 2016-06-18 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
NMR ID: | NM000039 |
Analysis ID: | AN000172 |
Instrument Name: | Bruker Avance III |
Instrument Type: | FT-NMR |
NMR Experiment Type: | 1D 1H |
Field Frequency Lock: | D20 |
Standard Concentration: | 1 mM |
Spectrometer Frequency: | 700 MHz |
NMR Probe: | 5mm Cryogenically Cooled ATMA |
NMR Solvent: | D20 |
NMR Tube Size: | 5mm |
Shimming Method: | Topshim (Gradient) |
Pulse Sequence: | cpmgpr1d |
Water Suppression: | yes |
Pulse Width: | 11.2 |
Power Level: | 25.704 W |
Receiver Gain: | 4.5 |
Offset Frequency: | 3300.70 Hz |
Chemical Shift Ref Cpd: | formate |
Temperature: | 298 K |
Number Of Scans: | 256 |
Dummy Scans: | 4 |
Acquisition Time: | 2.3243 |
Relaxation Delay: | 2s |
Spectral Width: | 20.13 ppm |
Num Data Points Acquired: | 65536 |
Real Data Points: | 65536 |
Line Broadening: | 0.5 |
Zero Filling: | Yes |
Apodization: | Lorentzian |
Baseline Correction Method: | Polynomial |
Chemical Shift Ref Std: | Formate |