Summary of Study ST000104

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000096. The data can be accessed directly via it's Project DOI: 10.21228/M8NK5J This work is supported by NIH grant, U2C- DK119886.

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Study IDST000104
Study TitleFactors for Epigenetic Silencing of Lung Cancer Genes
Study TypeMetabolomic analysis of Plasma
Study SummaryTo test the hypothesis that the propensity for silencing of tumor suppressor genes in the respiratory epithelium of chronic smokers by promoter hypermethylation is influenced by sequence variations that modify the activity of genes and microRNAÕs that directly or indirectly influence de novo methylation and chromatin remodeling.
Institute
University of North Carolina
DepartmentDiscovery Science Technology
LaboratorySumner Lab
Last NameSumner
First NameSusan
AddressEastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081
Emailsusan_sumner @unc.edu
Phone704-250-5066
Submit Date2014-09-29
Num Groups3
Total Subjects69
Raw Data AvailableYes
Raw Data File Type(s)fid
Uploaded File Size36 M
Analysis Type DetailNMR
Release Date2016-06-18
Release Version1
Susan Sumner Susan Sumner
https://dx.doi.org/10.21228/M8NK5J
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR000096
Project DOI:doi: 10.21228/M8NK5J
Project Title:Factors for Epigenetic Silencing of Lung Cancer Genes
Project Type:Metabolomics
Project Summary:To test the hypothesis that the propensity for silencing of tumor suppressor genes in the respiratory epithelium of chronic smokers by promoter hypermethylation is influenced by sequence variations that modify the activity of genes and microRNA’s that directly or indirectly influence de novo methylation and chromatin remodeling.
Institute:Lovelace Respiratory Research Institute
Department:Lung Cancer Program
Last Name:Belinsky
First Name:Steven
Address:Lovelace Respiratory Research Institute, 2425 ridgecrest Dr, SE, Albuqurque, NM
Email:SBelinsk@lrri.org
Phone:505-348-9465
Funding Source:NCI
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