Summary of Study ST000785

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000571. The data can be accessed directly via it's Project DOI: 10.21228/M8VM2M This work is supported by NIH grant, U2C- DK119886.

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Study IDST000785
Study TitlePharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock
Study Typemultiple timepoints; patients with severe sepsis or septic shock
Study Summaryphase I study of L-carnitine infusion for the treatment of vasopressor-dependent shock
Institute
University of Michigan
DepartmentClinical Pharmacy
LaboratoryThe NMR Metabolomics Laboratory (Stringer)
Last NameStringer
First NameKathleen
AddressUniversity Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105
EmailNMRmetabolomics@umich.edu
Phonenone
Submit Date2016-12-08
Num Groups2
Total Subjects31
Raw Data AvailableYes
Raw Data File Type(s)fid
Analysis Type DetailNMR
Release Date2017-10-03
Release Version1
Kathleen Stringer Kathleen Stringer
https://dx.doi.org/10.21228/M8VM2M
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR000822
Treatment Summary:Intravenous carnitine
Treatment Protocol Comments:Non-treatment group: equivalent volume of saline placebo
Treatment Compound:L-carnitine
Treatment Route:4g bolus followed by an 8g infusion over 12h
Treatment Dose:12g
Treatment Doseduration:12h (following initial 4g bolus)
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