MGP Database (Select MGP_ID for details on gene/protein of interest)

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MGP IDEntrez Gene IDEnzyme/ReactantsGene nameSymbol
MGP000024 39 2.3.1.9| Reactants acetyl-CoA acetyltransferase 2 ACAT2
MGP000777 1595 1.14.13.70| Reactants cytochrome P450, family 51, subfamily A, polypeptide 1 CYP51A1
MGP000827 1718 1.3.1.72| Reactants 24-dehydrocholesterol reductase DHCR24
MGP004332 10682 5.3.3.5| Reactants emopamil binding protein (sterol isomerase) EBP
MGP001053 2222 2.5.1.21| Reactants farnesyl-diphosphate farnesyltransferase 1 FDFT1
MGP001054 2224 2.5.1.10| Reactants farnesyl diphosphate synthase FDPS
MGP003911 9453 2.5.1.-| Reactants geranylgeranyl diphosphate synthase 1 GGPS1
MGP001466 3156 1.1.1.34;| Reactants 3-hydroxy-3-methylglutaryl-CoA reductase HMGCR
MGP001467 3157 2.3.3.10| Reactants 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) HMGCS1
MGP005195 51478 1.1.1.270| Reactants hydroxysteroid (17-beta) dehydrogenase 7 HSD17B7
MGP001557 3422 5.3.3.2| Reactants isopentenyl-diphosphate delta isomerase 1 IDI1
MGP001823 3988 3.1.1.13| Reactants lipase A, lysosomal acid, cholesterol esterase LIPA
MGP001840 4047 5.4.99.7| Reactants lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) LSS
MGP002751 6307 1.14.13.72| Reactants methylsterol monooxygenase 1 MSMO1
MGP001988 4597 4.1.1.33| Reactants mevalonate (diphospho) decarboxylase MVD
MGP001989 4598 2.7.1.36;| Reactants mevalonate kinase MVK
MGP005075 50814 1.1.1.170| Reactants NAD(P) dependent steroid dehydrogenase-like NSDHL
MGP004323 10654 2.7.4.2;| Reactants phosphomevalonate kinase PMVK
MGP002752 6309 1.14.21.6| Reactants sterol-C5-desaturase SC5D
MGP002949 6646 2.3.1.26| Reactants sterol O-acyltransferase 1 SOAT1
MGP002970 6713 1.14.13.132| Reactants squalene epoxidase SQLE
MGP003154 7108 1.3.1.70| Reactants transmembrane 7 superfamily member 2 TM7SF2
Metabolites in human pathway:Steroid Biosynthesis

MetaboliteHMDB pathwayKEGG pathway
24,25-dihydrolanosterol SMP00023 Reference  | Human
3-hydroxy-3-methylglutaryl-CoA SMP00023 Reference  | Human
3-dehydro-4-methylzymosterol SMP00023 Reference  | Human
4,4-dimethylcholesta-8,11,24-trienol SMP00023 Reference  | Human
4alpha-methylzymosterol SMP00023 Reference  | Human
Zymostenol SMP00023 Reference  | Human
7-dehydrocholesterol SMP00023 Reference  | Human
7-dehydro-desmosterol SMP00023 Reference  | Human
8-Dehydrocholesterol SMP00023 Reference  | Human
Acetoacetyl-CoA SMP00023 Reference  | Human
Acetyl-CoA SMP00023 Reference  | Human
ADP SMP00023 Reference  | Human
Adenosine triphosphate SMP00023 Reference  | Human
Cholesterol SMP00023 Reference  | Human
Coenzyme A SMP00023 Reference  | Human
Desmosterol SMP00023 Reference  | Human
Dimethylallyl-diphosphate SMP00023 Reference  | Human
FAD SMP00023 Reference  | Human
Farnesyl diphosphate SMP00023 Reference  | Human
Palmitic acid SMP00023 Reference  | Human
Formic acid SMP00023 Reference  | Human
Geranyl diphosphate SMP00023 Reference  | Human
Heme SMP00023 Reference  | Human
Isopentenyl-diphosphate SMP00023 Reference  | Human
Lanosterol SMP00023 Reference  | Human
Lathosterol SMP00023 Reference  | Human
Mevalonic acid SMP00023 Reference  | Human
5-phosphomevalonic acid SMP00023 Reference  | Human
NADP SMP00023 Reference  | Human
NADPH SMP00023 Reference  | Human
5-Diphosphomevalonic acid SMP00023 Reference  | Human
Squalene SMP00023 Reference  | Human
Zymosterol SMP00023 Reference  | Human
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